Research

Edwards DJ, Cortes M, Rykman-Peltz A, Chang J, Elder J, Thickbroom G, Mariman JJ, Gerber LM, Oromendia C, Krebs HI, Fregni F, Volpe BT, Pascual-Leone A. Clinical improvement with intensive robot-assisted arm training in chronic stroke is unchanged by supplementary tDCS. Restor Neurol Neurosci. 2019;37(2):167-180. doi: 10.3233/RNN-180869.​ https://pubmed.ncbi.nlm.nih.gov/30932903/ **could not find access to full text**

Wuennemann MJ, Mackenzie SW, Lane HP, Peltz AR, Ma X, Gerber LM, Edwards DJ, Kitago T. Dose and staffing comparison study of upper limb device-assisted therapy. NeuroRehabilitation. 2020 Mar 30. doi: 10.3233/NRE-192993. https://pubmed.ncbi.nlm.nih.gov/32250331/ **could not find access to full text**

Edwards DJ, Cortes M, Rykman-Peltz A, Chang J, Elder J, Thickbroom G, Mariman JJ, Gerber LM, Oromendia C, Krebs HI, Fregni F, Volpe BT, Pascual-Leone A. Clinical improvement with intensive robot-assisted arm training in chronic stroke is unchanged by supplementary tDCS.​ Restor Neurol Neurosci. 2019;37(2):167-180. doi: 10.3233/RNN-180869.​ ​https://pubmed.ncbi.nlm.nih.gov/30932903/ **could not find access to full text**

Adam Buchwald, Carolyn Falconer, Avrielle Rykman-Peltz, Mar Cortes, Alvaro Pascual-Leone, Gary W. Thickbroom, Hermano Igo Krebs, Felipe Fregni, Linda M. Gerber, Clara Oromendia, Johanna Chang, Bruce T. Volpe and Dylan J. Edwards Robotic Arm Rehabilitation in Chronic Stroke Patients With Aphasia May Promote Speech and Language Recovery (but Effect Is Not Enhanced by Supplementary tDCS) Front Neurol. 2018 Oct 22;9:853. doi: 10.3389/fneur.2018.00853. eCollection 2018.​ ​https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6207995/

Putrino D, Zanders H, Hamilton T, Rykman A, Lee P, Edwards DJ. Patient Engagement Is Related to Impairment Reduction During Digital Game-Based Therapy in Stroke. Games Health J. 2017 Oct;6(5):295-302. doi: 10.1089/g4h.2016.0108. Epub 2017 Sep 14.​ ​https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5911704/ Cortes M, Thickbroom GW, Elder J, Rykman A, Valls-Sole J, Pascual-Leone A, Edwards DJ. The corticomotor projection to liminally-contractable forearm muscles in chronic spinal cord injury: a transcranial magnetic stimulation study. Spinal Cord. 2017 Apr;55(4):362-366. doi: 10.1038/sc.2016.161. Epub 2016 Dec 20.​ ​https://www.nature.com/articles/sc2016161

Thickbroom GW, Cortes M, Rykman A, Volpe BT, Fregni F, Krebs HI, Pascual-Leone A, Edwards DJ. Stroke subtype and motor impairment influence contralesional excitability. Neurology. 2015 Aug 11;85(6):517-20. doi: 10.1212/WNL.0000000000001828.​ ​https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4540249/

Mar Cortes, MD, Gary W. Thickbroom, PhD, Avrielle Rykman, OT, Alvaro Pascual-Leone, MD, PhD, Dylan J. Edwards, PhD. Physiologic mapping and modeling of motor targets for neuromodulation in spinal cord injury. 1st International Brain Stimulation Conference; 2015 March; , Singapore. Elsevier; c2015.​ https://www.brainstimjrnl.com/article/S1935-861X(15)00800-1/fulltext **could not find access to full text**

Edwards DJ, Cortes M, Thickbroom GW, Rykman A, Pascual-Leone A, Volpe BT. Reply: evidence against volume conduction to explain normal MEPs in muscles with low motor power in SCI. Spinal Cord. 2014 Sep;52(9):718. doi: 10.1038/sc.2014.117. No abstract available. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5575983/

Krebs HI, Krams M, Agrafiotis DK, DiBernardo A, Chavez JC, Littman GS, Yang E, Byttebier G, Dipietro L, Rykman A, McArthur K, Hajjar K, Lees KR, Volpe BT. Robotic measurement of arm movements after stroke establishes biomarkers of motor recovery. Stroke. 2014 Jan;45(1):200-4. doi: 10.1161/STROKEAHA.113.002296. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4689592/pdf/nihms744804.pdf

Falconer C, Buchwald A, Edwards D, Cortes M, Rykman A, et al.  Speech-language neurorehabilitation: Preliminary results of tDCS and robotic arm training in single left ischemic stroke NYC Neuromodulation Conference; 2013 November; New York, New York, United States. Elsevier Inc.; c2014. https://www.sciencedirect.com/science/article/pii/S1935861X14000291

Elder J, Cortes M, Rykman A, Hill J, Karuppagounder S, Edwards D, Ratan RR. The epigenetics of stroke recovery and rehabilitation: from polycomb to histone deacetylases. Neurotherapeutics. 2013 Oct;10(4):808-16. doi: 10.1007/s13311-013-0224-3. Review. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3805866/pdf/13311_2013_Article_224.pdf

Boratyn D, Ruffini G, Cortes M, Rykman A, Medeiros A, Pascual-Leone A, Edwards DJ. Focal tDCS in Chronic Stroke patients: A pilot study of physiological effects using TMS and concurrent EEG 5th International Conference on Non-Invasive Brain Stimulation; 2013 March; Leipzig, Saxony, Germany. Elsevier; c2013.

Cortes M, Elder J, Rykman A, Murray L, Avedissian M, Stampas A, Thickbroom GW, Pascual-Leone A, Krebs HI, Valls-Sole J, Edwards DJ. Improved motor performance in chronic spinal cord injury following upper-limb robotic training. NeuroRehabilitation. 2013;33(1):57-65. doi: 10.3233/NRE-130928. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4519228/pdf/nihms666977.pdf

Giacobbe V, Krebs HI, Volpe BT, Pascual-Leone A, Rykman A, Zeiarati G, Fregni F, Dipietro L, Thickbroom GW, Edwards DJ. Transcranial direct current stimulation (tDCS) and robotic practice in chronic stroke: the dimension of timing. NeuroRehabilitation. 2013;33(1):49-56. doi: 10.3233/NRE-130927. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4515138/pdf/nihms666998.pdf

Edwards DJ, Cortes M, Thickbroom GW, Rykman A, Pascual-Leone A, Volpe BT. Preserved corticospinal conduction without voluntary movement after spinal cord injury. Spinal Cord. 2013 Oct;51(10):765-7. doi: 10.1038/sc.2013.74. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4514766/pdf/nihms605750.pdf

Volpe BT, Huerta PT, Zipse JL, Rykman A, Edwards D, Dipietro L, Hogan N, Krebs HI. Robotic devices as therapeutic and diagnostic tools for stroke recovery. Arch Neurol. 2009 Sep;66(9):1086-90. doi: 10.1001/archneurol.2009.182. Review. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5576183/pdf/nihms900193.pdf

Edwards DJ, Krebs HI, Rykman A, Zipse J, Thickbroom GW, Mastaglia FL, Pascual-Leone A, Volpe BT. Raised corticomotor excitability of M1 forearm area following anodal tDCS is sustained during robotic wrist therapy in chronic stroke. Restor Neurol Neurosci. 2009;27(3):199-207. doi: 10.3233/RNN-2009-0470. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4510929/pdf/nihms670025.pdf